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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 110, No. 2, 2015, pp. 242-248
Bioline Code: oc15030
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 110, No. 2, 2015, pp. 242-248

 en Biofilm production by multiresistant Corynebacterium striatum check for this species in other resources associated with nosocomial outbreak
de Souza, Cassius; Faria, Yuri Vieira; de Oliveira Sant’Anna, Lincoln; Viana, Vanilda Gonçalves; Seabra, Sérgio Henrique; de Souza, Mônica Cristina; Vieira, Verônica Viana; Júnior, Raphael Hirata; de Oliveira Moreira, Lílian & de Mattos-Guaraldi, Ana Luíza

Abstract

Corynebacterium striatum check for this species in other resources is a potentially pathogenic microorganism that causes nosocomial outbreaks. However, little is known about its virulence factors that may contribute to healthcare-associated infections (HAIs). We investigated the biofilm production on abiotic surfaces of multidrug-resistant (MDR) and multidrug-susceptible (MDS) strains of C. striatum of pulsed-field gel electrophoresis types I-MDR, II-MDR, III-MDS and IV-MDS isolated during a nosocomial outbreak in Rio de Janeiro, Brazil. The results showed that C. striatum was able to adhere to hydrophilic and hydrophobic abiotic surfaces. The C. striatum 1987/I-MDR strain, predominantly isolated from patients undergoing endotracheal intubation procedures, showed the greatest ability to adhere to all surfaces. C. striatum bound fibrinogen to its surface, which contributed to biofilm formation. Scanning electron microscopy showed the production of mature biofilms on polyurethane catheters by all pulsotypes. In conclusion, biofilm production may contribute to the establishment of HAIs caused by C. striatum.

Keywords
biofilm; Corynebacterium striatum; epidemic clone; fibrinogen; multi-resistance; nosocomial outbreak

 
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