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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 110, No. 4, 2015, pp. 569-572
Bioline Code: oc15073
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 110, No. 4, 2015, pp. 569-572

 en First report of autochthonous transmission of Zika virus in Brazil
Zanluca, Camila; de Melo, Vanessa Campos Andrade; Mosimann, Ana Luiza Pamplona; dos Santos, Glauco Igor Viana; dos Santos, Claudia Nunes Duarte & Luz, Kleber

Abstract

In the early 2015, several cases of patients presenting symptoms of mild fever, rash, conjunctivitis and arthralgia were reported in the northeastern Brazil. Although all patients lived in a dengue endemic area, molecular and serological diagnosis for dengue resulted negative. Chikungunya virus infection was also discarded. Subsequently, Zika virus (ZIKV) was detected by reverse transcription-polymerase chain reaction from the sera of eight patients and the result was confirmed by DNA sequencing. Phylogenetic analysis suggests that the ZIKV identified belongs to the Asian clade. This is the first report of ZIKV infection in Brazil.

Keywords
Zika virus; “dengue-like syndrome”; Brazil

 
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