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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 110, No. 5, 2015, pp. 684-686
Bioline Code: oc15092
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 110, No. 5, 2015, pp. 684-686

 en Effects of penicillin and erythromycin on adherence of invasive and noninvasive isolates of Streptococcus pyogenes check for this species in other resources to laminin
Šmitran, Aleksandra; Vuković, Dragana; Gajić, Ina; Marinković, Jelena & Ranin, Lazar

Abstract

This study investigated the possible relationship between the invasiveness of group A Streptococcus (GAS) strains and their abilities to adhere to laminin and assessed the effects of subinhibitory concentrations of penicillin and erythromycin on the ability of GAS to adhere to laminin. The adherence of noninvasive and highly invasive isolates of GAS to laminin was significantly higher than the adherence displayed by isolates of low invasiveness. Antibiotic treatment caused significant reductions in adherence to laminin in all three groups of strains. Penicillin was more successful in reducing the adherence abilities of the tested GAS strains than erythromycin.

Keywords
Streptococcus pyogenes; adherence; laminin; penicillin; erythromycin

 
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