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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 111, No. 1, 2016, pp. 79-81
Bioline Code: oc16010
Full paper language: English
Document type: Report
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 111, No. 1, 2016, pp. 79-81

 en The mitogenome of Onchocerca volvulus from the Brazilian Amazonia focus
Crainey, James L.; Silva, Túllio R.R. da; Encinas, Fernando; Marín, Michel A.; Vicente, Ana Carolina P. & Luz, Sérgio L.B.


We report here the first complete mitochondria genome of Onchocerca volvulus from a focus outside of Africa. An O. volvulus mitogenome from the Brazilian Amazonia focus was obtained using a combination of highthroughput and Sanger sequencing technologies. Comparisons made between this mitochondrial genome and publicly available mitochondrial sequences identified 46 variant nucleotide positions and suggested that our Brazilian mitogenome is more closely related to Cameroon-origin mitochondria than West African-origin mitochondria. As well as providing insights into the origins of Latin American onchocerciasis, the Brazilian Amazonia focus mitogenome may also have value as an epidemiological resource.

Onchocerca volvulus mitochondria; onchocerciasis; Brazilian Amazonia focus; mitogenome

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