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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060 EISSN: 1678-8060
Vol. 111, No. 12, 2016, pp. 765-769
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Bioline Code: oc16122
Full paper language: English
Document type: Short Communication
Document available free of charge
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Memórias do Instituto Oswaldo Cruz, Vol. 111, No. 12, 2016, pp. 765-769
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Genomic and phylogenetic evidence of VIPER retrotransposon domestication in trypanosomatids
Ludwig, Adriana & Krieger, Marco Aurelio
Abstract
Transposable elements are important residents of eukaryotic genomes and eventually the host can domesticate
them to serve cellular functions. We reported here a possible domestication event of the vestigial interposed retroelement
(VIPER) in trypanosomatids. We found a large gene in a syntenic location in Leishmania braziliensis, L.
panamensis, Leptomanas pyrrhocoris, and Crithidia fasciculata whose products share similarity in the C-terminal
portion with the third protein of VIPER. No remnants of other VIPER regions surrounding the gene sequence were
found. We hypothesise that the domestication event occurred more than 50 mya and the conservation of this gene
suggests it might perform some function in the host species.
Keywords
transposable element; trypanosomatids; domestication; reverse transcriptase; evolution
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