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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 112, No. 2, 2017, pp. 81-93
Bioline Code: oc17011
Full paper language: English
Document type: Review Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 112, No. 2, 2017, pp. 81-93

 en Microbial control of arthropod-borne disease
Saldaña, Miguel A; Hegde, Shivanand & Hughes, Grant L

Abstract

Arthropods harbor a diverse array of microbes that profoundly influence many aspects of host biology, including vector competence. Additionally, symbionts can be engineered to produce molecules that inhibit pathogens. Due to their intimate association with the host, microbes have developed strategies that facilitate their transmission, either horizontally or vertically, to conspecifics. These attributes make microbes attractive agents for applied strategies to control arthropod-borne disease. Here we discuss the recent advances in microbial control approaches to reduce the burden of pathogens such as Zika, Dengue and Chikungunya viruses, and Trypanosome check for this species in other resources and Plasmodium check for this species in other resources parasites. We also highlight where further investigation is warranted.

Keywords
microbiome; paratransgenesis; mosquito; arbovirus; vector control; malaria

 
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