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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060 EISSN: 1678-8060
Vol. 113, No. 1, 2018, pp. 1-3
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Bioline Code: oc18003
Full paper language: English
Document type: Research Article
Document available free of charge
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Memórias do Instituto Oswaldo Cruz, Vol. 113, No. 1, 2018, pp. 1-3
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Evaluation of melanin production by Sporothrix luriei
Cruz, Ingrid Ludmilla Rodrigues; Figueiredo-Carvalho, Maria Helena Galdino; Zancopé-Oliveira, Rosely Maria & Almeida-Paes, Rodrigo
Abstract
There is a paucity of studies on the cell biology of Sporothrix luriei, the less common of the pathogenic Sporothrix
species worldwide. The production of DHN-melanin, eumelanin, and pyomelanin were evaluated on the mycelial
and yeast forms of the S. luriei ATCC 18616 strain. The mycelial form of this species produced only pyomelanin,
which protected the fungus against environmental stressors such as ultraviolet light, heat, and cold. The yeast form
was unable to produce any of the tested melanin types. The lack of melanin in the parasitic form of S. luriei may be
an explanation for its low frequency in human infections.
Keywords
Sporothrix luriei; L-tyrosine; pyomelanin
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