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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 89, No. 1, 1994, pp. 41-45
Bioline Code: oc94008
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 89, No. 1, 1994, pp. 41-45

 en Trypanosoma cruzi check for this species in other resources Infection in the Opossum Didelphis marsupialis check for this species in other resources : Absence of Neonatal Transmission and Protection by Maternal Antibodies in Experimental Infections
Ana M Jansen; Fatima B Madeira & Maria P Deane

Abstract

The high rate of natural  Trypanosoma  cruzi
  check for this species in other resources
 infection found in opossums does not always correlate with appreciable densities of local triatomid populations. One alternative method which might bypass the invertebrate vector is direct transmission from mother to offspring. This possibility was investigated in
five T. cruzi infected females and their litters (24 young).
The influence of maternal antibodies transferred via
lactation, on the course of experimental infection, was also
examined. Our results show that neonatal transmission is
probably not responsible for the high rate of natural T. cruzi
infection among opossums.

In addition antibodies of maternal origin confer a partial protection to the young. This was demonstrated by the finding of a double prepatency period and 4, 5 fold lower levels of circulating parasites, in experimentally infected pouch young from infected as compared to control uninfected mothes. On the other hand, the duration of patent parasitemia was twice as long as that observed in the control group.

Keywords
Trypanosoma cruzi - Didelphis marsupialis - opossum - antibodies - protection - neonatal transmission

 
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