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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 91, No. 1, 1996, pp. 101-105
Bioline Code: oc96017
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 91, No. 1, 1996, pp. 101-105

 en Analysis of the clonal diversity of staphylococcus aureus methicillin-resistant strains isolated at joao pessoa, state of paraiba, brazil
Filho, Lauro Santos; Sader, Helio Silva; Bortolotto, Vania I; Filho, Paulo P Gontijo & Pignatari, Antonio C

Abstract

To investigate the clonal diversity of  Staphylococcus  aureus strains isolated at Joao Pessoa, State of Paraiba, Brazil, digested genomic DNA were studied by pulsed-field gel electrophoresis (PFGE) in nine methicillin-resistant strains (MRSA) and three methicillin-sensitive strains (MSSA), selected among 67 isolates based on their antimicrobial susceptibility and epidemiology. The isolates were obtained between April and November 1992 from the Hospital of the Federal University of Paraiba, located in Joao Pessoa. Two MRSA isolates from the Oswaldo Cruz Hospital, Sao Paulo, Brazil, including an epidemic strain previously detected from different hospitals at the country were used as control. Five different patterns, were demonstrated by MRSA  isolated in Joao Pessoa and these patterns were described in several 
epidemiologically unrelated hospitals in Sao Paulo. Our results suggest the interstate dissemination of a MRSA clone in Joao Pessoa which is similar to that described in other cities of Brazil.

Keywords
Staphylococcus aureus - molecular epidemiology - antimicrobial resistance

 
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