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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 91, No. 3, 1996, pp. 285-291
Bioline Code: oc96057
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 91, No. 3, 1996, pp. 285-291

 en Biological Comparison between Three Clones of Trypanosoma cruzi and the Strain of Origin (Bolivia) with Reference to Clonal Evolution Studies
P Penin; C Gamallo & JA de Diego

Abstract

After isolating three clones of Trypanasoma cruzi
(Bolivia), we first characterized them according to
parasitaemia, pleomorphism and virulence, and then
histopathologically. The study's interest lies on the hypothesis
that clonal evolution of  T. cruzi  has a major impact on
biologically relevant properties of this parasite. Data obtained
from the studies of parasitaemia, pleomorphism and virulence
showed no differences between the groups studied. As a final
point, the histopathological study shows us a muscular  tissue
tropism both in clones and in their mother strain (Bolivia). In
this paper, we conclude that Bolivia strain and clones  isolated
from it, pertaining to the same major clone share similar
biological properties.

Keywords
Trypanosoma cruzi - histopathological study - clonal variability - biological characterization

 
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