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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 91, No. 5, 1996, pp. 621-625
Bioline Code: oc96112
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 91, No. 5, 1996, pp. 621-625

 en Rabies Virus Infection of Cultured Adult Mouse Dorsal Root Ganglion Neurons
Jaime Castellanos; Hernan Hurtado; Janeth Arias & Alvaro Velandia

Abstract

An in vitro model of adult dorsal root ganglion neurons
infection by rabies virus is described. Viral marked
neurotropism is observed, and the percentage and the degree of
infection of the neurons is higher than in non neuronal cells,
even if neurons are the minority of the cells in the culture.
The neuritic tree is also heavily infected by the virus.

Keywords
adult mouse - cell culture - dorsal root ganglion - infection - neuron - neurotropism - rabies

 
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