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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 92, No. 4, 1997, pp. 437-457
Bioline Code: oc97080
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 92, No. 4, 1997, pp. 437-457

 en Markers, cofactors and staging systems in the study of HIV disease progression: A review
MC Portela & KN Simpson

Abstract

This paper is aimed at providing a comprehensive review of markers,
cofactors and staging systems used for HIV disease, focusing on some
aspects that nowadays could even be considered historical, and advancing in
current issues such as the prognostic value of viral load measurements,
viral genotypic and phenotypic characterization, and new HIV disease
treatment protocols. CD4^+ cell values, combined with the new viral markers
mentioned are promising as a parsimonious predictor set for defining both
severity and progression. An adequate predictor of patient resource use for
planning purposes still needs to be defined.

Keywords
HIV disease progression - markers - cofactors - staging systems - AIDS classification systems

 
© Copyright 1997 Fundacao Oswaldo Cruz
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