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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 92, No. 5, 1997, pp. 619-623
Bioline Code: oc97116
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 92, No. 5, 1997, pp. 619-623

 en Effects of Bayluscide WP 70^R on the survival and water-leaving behaviour of Biomphalaria straminea, snail host of schistosomiasis in North-east Brazil
Otilia Sarquis; Otavio S Pieri & Jose Augusto A dos Santos

Abstract

The toxic and behavioural effects of niclosamide (Bayluscide WP 70^R) on
Biomphalaria straminea from a highly endemic area of schistosomiasis in
northeastern Brazil were investigated through laboratory bioassays. The
LD50 and LD90 were 0.114 mg/l and 0.212 mg/l, respectively. Water-leaving
behaviour occurred among 14% to 30% of the snails in the presence of
sublethal doses of niclosamide and among 16% of the controls. It was
concluded that both the relatively low susceptibility to niclosamide and
water-leaving behaviour of local B. straminea may be responsible for
the recolonization of transmission foci after mollusciciding. It was
suggested that recently improved measures of snail control, such as
controlled-release formulations of niclosamide and plant molluscicides
should be considered in areas where snail control is recommended.

Keywords
schistosomiasis - snail control - molluscicide - Bayluscide^R - Biomphalaria straminea

 
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