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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 92, No. 6, 1997, pp. 797-802
Bioline Code: oc97149
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 92, No. 6, 1997, pp. 797-802

 en Induction of glutathione S-transferase activity in Triatoma infestans
JL Sivori; N Casabe; EN Zerba & EJ Wood

Abstract

Several synthetic pesticides and allelochemicals used to treat Triatoma
infestans adults by topic application showed some degree of cytosolic
glutathione S-transferase (GST) induction. General inducers of detoxication
systems such as phenobarbital and 3-methylcholantrene topically applied on
T. infestans resulted in no GST induction. Meanwhile, general insecticide
synergist such as piperonyl butoxide (160 mg/insect) increased the
GST-activity in the range of 120-140%. 

Insects injected with reduced glutathione (300 mg/insect) presented at the forth day elevated GST activity.

Keywords
Triatoma infestans - glutathione S-transferase - induction

 
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