About Bioline  All Journals  Testimonials  Membership  News  Donations

Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 93, No. 2, 1998, pp. 215-217
Bioline Code: oc98041
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 93, No. 2, 1998, pp. 215-217

 en The growth of brown adipose tissue in cold-acclimatized rats after Depletion of mast cell histamine by compound 48/80
Nelson L Dalo; Aura A Lopez-Ortega & Haity Moussatche


Cold acclimatization (4-5 C) is accompanied by 2-3 fold increase of
brown adipose tissue (BAT). This rapid growth of interscapular BAT was
studied after histamine depletion. In control rats maintained at room
temperature (28 +/- 2 C) the BAT histamine content was 23.4 +/- 5.9 (mean
+/- SD) ug/g of tissue and cold acclimatization (5+/-1 C) produced a
significant increase of BAT weight, but reduced the histamine content to
8.4 +/- 1.9 ug/g. The total weight of BAT after 20 days of acclimatization
was unaffected by depletion of histamine due to compound 48/80. The low
level of histamine in BAT of cold acclimatized rats could be due to a fast
rate of amine utilization; alternatively an altered synthesis or storage
process may occur during acclimatization.

cold acclimatization - brown adipose tissue - histamine - tissue growth

© Copyright 1998 Fundacao Oswaldo Cruz - Fiocruz
Alternative site location:

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2018, Site last up-dated on 09-Jul-2018.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Internet Data Center of Rede Nacional de Ensino e Pesquisa, RNP, Brazil