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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 93, No. 3, 1998, pp. 407-409
Bioline Code: oc98079
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 93, No. 3, 1998, pp. 407-409

 en Serological evidence of HTLV-I and HTLV-II coinfections in HIV-1 positive patients in Belem, State of Para, Brazil
ACR Vallinoto; VN Azevedo; DEM Santos; S Caniceiro; FCL Mesquita; WW Hall; MOG Ishak & R Ishak

Abstract

The occurrence of HTLV-I/II and HIV-1 coinfections have been shown to be
frequent, probably in consequence of their similar modes of transmission.
This paper presents the prevalence of coinfection of HTLV among HIV-1
infected and AIDS patients in Belem, State of Para, Brazil. A group of 149
patients attending the AIDS Reference Unit of the State Department of
Health was tested for the presence of antibodies to HTLV-I/II using an
enzyme immunoassay and the positive reactions were confirmed with a Western
blot that discriminates between HTLV-I and HTLV-II infections. Four
patients (2.7%) were positive to HTLV-I, seven (4.7%) to HTLV-II and one
(0.7%) showed an indeterminate pattern of reaction. The present results
show for the first time in Belem not only the occurrence of HTLV-II/HIV-1
coinfections but also a higher prevalence of HTLV-II in relation to HTLV-I.
Furthermore, it also enlarges the geographical limits of the endemic area
for HTLV-II in the Amazon region of Brazil.

Keywords
HIV - HTLV - coinfection - retrovirus

 
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