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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 94, No. 2, 1999, pp. 189
Bioline Code: oc99040
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 94, No. 2, 1999, pp. 189

 en Characterization of Trypanosoma rangeli Strains Isolated in Central and South America: an Overview
Edmundo C Grisard; Mário Steindel; Alessandra A Guarneri; Iriane Eger-Mangrich; David A Campbell & Alvaro J Romanha

Abstract

Trypanosoma rangeli is a hemoflagelate parasite that infects domestic and sylvatic animals, as well as man, in Central and South America. T. rangeli has an overlapping distribution with {B}T. cruzi{/B}, the etiological agent of Chagas disease, sharing several animal reservoirs and triatomine vectors. We have isolated T. rangeli strains in the State of Santa Catarina, in southern Brazil, which dramatically increased the distribution area of this parasite. This brief review summarizes
several studies comparing T. rangeli strains isolated in Santa Catarina with others isolated in Colombia, Honduras and Venezuela. The different methods used include indirect immunofluorescence and western blot assays, lectin agglutination, isoenzyme electrophoresis and random amplified polymorphic DNA
analysis, triatomine susceptibility, in vitro cell infection assays, and mini-exon gene analysis.

Keywords
Trypanosoma rangeli - antigens - carbohydrates - random amplified polymorphic DNA - isoenzymes - mini-exon gene - triatomine susceptibility

 
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