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Memórias do Instituto Oswaldo Cruz
Fundação Oswaldo Cruz, Fiocruz
ISSN: 1678-8060
EISSN: 1678-8060
Vol. 94, No. 2, 1999, pp. 255-260
Bioline Code: oc99050
Full paper language: English
Document type: Research Article
Document available free of charge

Memórias do Instituto Oswaldo Cruz, Vol. 94, No. 2, 1999, pp. 255-260

 en Clinical, Parasitological and Immunological Aspects of Experimental Infection with Trypanosoma evansi in Dogs
Lúcia Padilha Cury Thomaz de Aquino; Rosangela Zacarias Machado; Antônio Carlos Alessi; Luiz Carlos Marques; Márcio Botelho de Castro & Euclides Braga Malheiros

Abstract

This research investigated the pattern of antibody response by means of enzyme linked immunosorbent assay (Elisa) and indirect fluorescent antibody test (IFAT) through the course of experimental Trypanosoma evansi infection in dogs. Clinical and parasitological features were also studied. The average prepatent period was 11.2 days and parasitaemia showed an undulating course. Biometrical study of parasites revealed a mean total length of 21.68mm. The disease was characterized by intermittent fever
closely related to the degree of parasitaemia and main clinical signs consisted of pallor of mucous membrane, edema, progressive emaciation and enlargement of palpable lymph nodes. Diagnostic antibody was detected within 12 to 15 days and 15 to 19 days of infection by IFAT and Elisa, respectively. High and persistent antibody levels were detected by both tests and appeared not to correlate with control of parasitaemia

Keywords
Trypanosoma evansi - dogs - biometry - Elisa - inmunofluorescent antibody test - clinical features

 
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