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Indian Journal of Occupational and Environmental Medicine
Medknow Publications
ISSN: 0973-2284 EISSN: 0973-2284
Vol. 11, No. 2, 2007, pp. 80-82
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Bioline Code: oe07017
Full paper language: English
Document type: Research Article
Document available free of charge
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Indian Journal of Occupational and Environmental Medicine, Vol. 11, No. 2, 2007, pp. 80-82
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Brief Communication - Reversible delayed neuropsychiatric syndrome following acute carbon monoxide exposure
Bhatia, R.; Chacko, F.; Lal, V. & Mittal, B.R.
Abstract
A 40-year-old male presented with acutely oncoming neuropsychiatric symptoms in the form of extrapyramidal disturbances, personality change, behavior changes and urinary incontinence. One month prior to this symptomatology, he had been found unconscious in his closed room where a coal fire was burning overnight. He recovered completely in two days with supportive therapy. Magnetic resonance imaging during this presentation showed bilateral white matter changes suggestive of demyelination. Tc99m-ECD SPECT study revealed hypoperfusion in bilateral frontal region. He was managed conservatively and eventually made a nearly complete recovery. Repeat SPECT study revealed marked improvement in tracer uptake correlating with his improvement. Delayed neuropsychiatric syndrome after acute carbonmonoxide poisoning is a rare and distinct entity. This case report discusses the various aspects of this disease entity.
Keywords
Carbonmonoxide poisoning, demyelination
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© Copyright 2007 Indian Journal of Occupational and Environmental Medicine. Alternative site location: http://www.ijoem.com
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