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Caries prevalence, level of mutans streptococci, salivary flow rate, and buffering capacity in subjects with Down syndrome
de Castilho, Aline Rogéria Freire; Pardi, Vanessa & Pereira, Cássio Vicente
Abstract
The aim of this study was to correlate caries experience and
physiological and microbiological profiles. The study group comprised
60 individuals with Down syndrome, both genders, aged from one to
48 years. The prevalence of caries was analyzed by DMFT/DMFS
and dmft/dmfs indexes. Physiological factors such as flow rate, and
buffer capacity and microbiological factor such as mutans streptococci
counts were observed. The average DMFT and DMFS were,
respectively, 4.53 and 6.85, whereas the mean dmft and dmfs values
were 1.55 and 2.55, respectively. Ninety-four percent of 18 individuals
that saliva was possible to collected presented low flow rate and only
6% of them had normal flow rate; 44% percent had low buffer capacity,
39% had limited buffer capacity and 16% had normal buffer capacity.
Sixty percent of individuals had high values of CFU/mL (>1.000.000
S. mutans); while 40% presented low values of microorganisms
(<100.000 S. mutans). Data of clinical, physiological and
microbiological characterization were statistically analyzed through
Pearson’s correlation and Chi-square test. A p-value d” 0.05 was
considered significant. DMFT/DMTS and dmft/dmfs indexes
increased with age. Pearson’s correlation showed significant values to
DMFT/DMFS x age (r= 0.80 and r= 0.82; p < 0.01). Flow rate and
buffering capacity were low. Individuals had high mutans streptococci
counts (CFU/mL). DMFT/DMFS did not present significant
correlation with flow rate, buffering capacity and mutans streptococci
counts and no association with gender. The prevalence of dental caries
increased with age at individuals with Down syndrome. As caries is a
multifactor disease, other factors, which were not evaluated in the
present study, such as diet, host and oral hygiene might be influencing
the development of dental caries in these individuals.
Keywords
caries, flow rate, buffer capacity, mutans streptococci, Down syndrome
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