Influence of dialysis duration and parathyroid hormone on the clinical and radiographic oral conditions of pre-transplant patients with chronic kidney disease|
Medeiros Queiroz, Stênio; Gomes Amorim, Adriana; de Andrade; Ana Luiza Dias Leite; Gordón-Núñez, Manuel Antonio; de Almeida Freitas, Roseana & Galvão, Hébel Cavalcanti
Aim: To evaluate the oral conditions of patients with chronic kidney disease undergoing dialysis
and to determine the influence of dialysis duration and bone metabolism on the prevalence and
severity of the alterations found.
Methods: The simplified oral hygiene index (OHI-S), prevalence
of dental caries (decayed, missing filled teeth index, DMFT), and the periodontal screening and
recording (PSR) index were evaluated in 154 patients. Parathyroid hormone (PTH), calcium,
phosphorus and urea measurements, as well as panoramic radiographs, were obtained from all
patients. To evaluate the effect of duration of dialysis treatment on oral health, the patients were
divided into two groups: (1) <5 years and (2) > 5 years. Regarding blood levels of PTH, patients
were divided into three groups: (1) 0-149 pg/mL, (2) 150-584 pg/mL, and (3) >585 pg/mL. The
OHI-S identified the accumulation of biofilm and calculus around the teeth.
inflammation was found in 100% of dentate patients, with 2 being the predominant PSR score
(72.3%). The DMFT index was high (17.52). Dental calculus was the most common radiographic
finding (70.8%). No significant correlation was observed between dialysis duration, biochemical
alterations, and oral health.
Conclusions: Most patients undergoing dialysis presented precarious
oral hygiene, periodontal inflammation, and bone alterations. However, these manifestations
were not influenced by the duration of dialysis or bone metabolism.
chronic kidney disease, parathyroid hormone, oral health, hemodialysis