Brazilian Journal of Oral Sciences
Piracicaba Dental School - UNICAMP
Vol. 12, No. 3, 2013, pp. 169-172
Bioline Code: os13034
Full paper language: English
Document type: Research Article
Document available free of charge
Brazilian Journal of Oral Sciences, Vol. 12, No. 3, 2013, pp. 169-172
© Brazilian Journal of Oral Sciences
Profile of salivary gland flow dysfunctions in patients with differentiated thyroid carcinoma submitted to radioiodine therapy|
Vieira, Anna Clara Fontes; Rodrigues, Aline Sampaio Lima; da Cruz, Maria Carmen Fontoura Nogueira & Lopes, Fernanda Ferreira
Aim: To evaluate the effects of radioiodine therapy on salivary flow in patients with differentiated
Methods: A sample comprising 88 patients submitted to ablation with iodine 131
was included in the study. The patients were submitted to sialometry and evaluation of the
presence of xerostomia before, 10 days and 3 months after radioiodine therapy.
Xerostomia was observed in 36.4% of the patients before radioiodine therapy, 59.15% at 10
days after therapy, and 25% at 3 months after therapy. Significant differences were observed in
non-stimulated salivary flow rates between the second and third evaluations (p≤0.020) and in
stimulated salivary flow between the first and second evaluations (p≤0.010).
results suggest that changes in salivary flow resulting from radioiodine therapy are more
pronounced during the first weeks after treatment and seem to regress after 3 months.
thyroid gland tumors; iodine radioisotopes; salivary glands; saliva; xerostomia; hyposalivation
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