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Brazilian Journal of Oral Sciences
Piracicaba Dental School - UNICAMP
EISSN:
Vol. 12, No. 4, 2013, pp. 345-351
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Bioline Code: os13058
Full paper language: English
Document type: Research Article
Document available free of charge
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Brazilian Journal of Oral Sciences, Vol. 12, No. 4, 2013, pp. 345-351
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Use of etoricoxib and dexamethasone for postoperative pain prevention and control in mucogingival surgery - A randomized parallel double-blind clinical trial
Zardo, Ligia Nadal; dos Santos, Fábio André & Pilatti, Gibson Luiz
Abstract
Aim: To compare the use of etoricoxib and dexamethasone for postoperative pain prevention
and control after mucogingival surgery. Methods: Fifty-eight patients with indication for
mucogingival surgery took part in this randomized parallel double-blind clinical trial. They were
divided into three groups (G): G1 – placebo 1 h before surgery; G2 – 8 mg dexamethasone 1
h before surgery; G3 – 90 mg etoricoxib 1 h before surgery. Pain intensity was assessed in
donor and recipient sites separately using the 101-point numerical rating scale NRS – 101,
every hour for the first 8 h after surgery and three times a day on the following 3 days. Results:
there was a statistically significant difference in the postoperative pain intensity in the donor site
between G1 and G3 after 1 h, 2 h, 3 h, 7 h, 8 h and on the second day – in the evening after 32
h; between G1 and G2 after 2 h and 3 h, and between G2 and G3 only after the first hour. Pain
intensity in the recipient site was statistically significant between G1 and G3 after 1 and 2 h
(p<0.05). In addition, there was a lower ingestion of rescue medication in G2 and in G3 than in
G1 (p=0.002). Conclusions: the use of a pre-emptive single dose of etoricoxib or
dexamethasone may be considered an effective protocol for postoperative pain prevention and
control after mucogingival surgery.
Keywords
analgesia; pain; postoperative; surgery; oral
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