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Brazilian Journal of Oral Sciences
Piracicaba Dental School - UNICAMP
EISSN:
Vol. 13, No. 1, 2014, pp. 47-52
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Bioline Code: os14010
Full paper language: English
Document type: Research Article
Document available free of charge
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Brazilian Journal of Oral Sciences, Vol. 13, No. 1, 2014, pp. 47-52
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Influence of ovariectomy combined with lack of masticatory force in the evolution of periodontal disease
Milhan, Noala Vicensoto Moreira; de Brito Penna Forte, Lilibeth Ferraz; de Vasconcelos, Luana Marotta Reis; Balducci, Ivan & Carvalho, Yasmin Rodarte
Abstract
Aim: To evaluate the influence of ovariectomy combined with lack of masticatory force in the
evolution of periodontal disease induced in rats. Methods: Forty rats were bilaterally
ovariectomized and 40 were submitted to sham ovariectomy. Periodontal disease was induced in
the mandibular left first molar and the maxillary left first molar was extracted from half of the rats. The
rats were randomly euthanized at 3, 7, 14 and 30 days post periodontal disease induction. Serial
sections were obtained from the furcation area and stained for histological and histomorphometric
analysis. The results of the histomorphometric analysis were statistically analyzed by ANOVA and
Tukey tests. Results: The results demonstrated statistically significant differences in the percentage
of bone tissue when the variables presence or absence of estrogen (p=0.020) and time of
euthanasia (p=0.002) were evaluated. However, the extraction procedure did not significantly
affect the percentage of bone tissue (p=0.598). Conclusions: The bone loss resulting from
periodontal disease is increased by estrogen deficiency and varies according to the time course
of periodontitis. In contrast, masticatory force does not seem to interfere in bone loss derived from
periodontal disease.
Keywords
ovariectom; periodontal diseases
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© Brazilian Journal of Oral Sciences Alternative site location: http://www.fop.unicamp.br/brjorals
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