search
for
 About Bioline  All Journals  Testimonials  Membership  News  Donations


Iranian Journal of Pediatrics
Tehran University of Medical Sciences Press
ISSN: 1018-4406
EISSN: 2008-2150
Vol. 17, No. 1, 2007, pp. 47-51
Bioline Code: pe07009
Full paper language: English
Document type: Research Article
Document available free of charge

Iranian Journal of Pediatrics, Vol. 17, No. 1, 2007, pp. 47-51

 en Seroprevalence of Hepatitis A in 7-10 year-old children
Kazemi, Seyed Alinaghi; Mahram, Manoochehr; Koosha, Ali & Amirmoghaddami, Hamid Reza

Abstract


Objective: Hepatitis A is one of the most common infections during childhood, especially in developing countries. Regarding the high prevalence of the disease in Iran, this study was performed to detect the rate of the contact of the children of Zanjan/Iran with the virus of hepatitis A (HAV).
Material & Methods: In a cross-sectional study, total anti HAV was assayed by ELISA method in serum samples of 300 children, aged 7-10 years, selected by multistage random sampling. The results were statistically analyzed. 27 children did not agree to participate in the study.
Findings: Out of 273 samples, including 134 males and 139 females, 121 children (44.3%) had serum antibody against Hepatitis A. Of these children, 42%, 45.4% and 45.3% were 7-8, 8-9 and 9-10 years of age, respectively. No significant difference was found among age groups or between sex groups.
Conclusion: According to this study, 44.3% of 7-10 year-old children have had previous contact with hepatitis A virus. This shows a high rate of seronegativity and sensitivity in adult community. Therefore, especially with regard to the high frequency of travels of the people between Iran and neighboring countries, that have high prevalence of disease, revision of national prevention protocol is recommended.

Keywords
Anti-HAV , Children , Hepatitis A , Viral infection

 
© Copyright 2007 - TUMS PUBLICATIONS
Alternative site location: http://diglib.tums.ac.ir/pub/

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2017, Site last up-dated on 16-Oct-2017.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Internet Data Center of Rede Nacional de Ensino e Pesquisa, RNP, Brazil