Iranian Journal of Pediatrics
Tehran University of Medical Sciences Press
Vol. 21, No. 3, 2011, pp. 271-277
Bioline Code: pe11047
Full paper language: English
Document type: Research Article
Document available free of charge
Iranian Journal of Pediatrics, Vol. 21, No. 3, 2011, pp. 271-277
© Copyright 2011 Iran Journal of Pediatrics.
Growth Impairment and Nutritional Status in Children with Chronic Kidney Disease|
Sozeri, Betul; Mir, Sevgi; Kara, Orhan Deniz & Dincel, Nida
Objective: Malnutrition is closely linked to chronic kidney disease (CKD) in adult patients with poor
outcome. But data on pediatric patients is inadequate. The aim of this study was to describe the
prevalence of growth failure and malnutrition in pediatric CKD patients and explore the relationship
of these parameters to each other and to other clinical parameters.
Methods: This study included 42 patients and 29 healthy children matched for age and gender.
Patients were classified firstly in age group and secondly in therapy modalities. Nutritional
evaluations were performed according to the Kidney Disease Outcomes Quality Initiative guidelines,
and we performed adjustments using values from children with the same chronological age as
Findings: In pubertal group, the mean height SDS was lower than in pre-pubertal period while it was
higher than in early childhood (P=0.4 and P=0.03 respectively). In all groups, 45% of patients had
malnutrition: 20 patients on predialysis, 22 patients with end stage renal disease (14 on
hemodialysis, and 8 on peritoneal dialysis). The mean weight SDS was lower in end stage renal
disease groups (P<0.001). The height SDS was lower in end stage renal disease groups (P<0.001).
Conclusion: Growth failure and malnutrition remain a significant clinical problem as age and therapy
modalities are dependent in children with CKD.
Chronic Kidney Disease; Renal Replacement Therapy; Malnutrition; Growth
Alternative site location: http://diglib.tums.ac.ir/pub/