Iranian Journal of Pediatrics
Tehran University of Medical Sciences Press
Vol. 21, No. 3, 2011, pp. 294-300
Bioline Code: pe11050
Full paper language: English
Document type: Research Article
Document available free of charge
Iranian Journal of Pediatrics, Vol. 21, No. 3, 2011, pp. 294-300
© Copyright 2011 Iran Journal of Pediatrics.
Prevalence of Asthma in Children of Chemical Warfare Victims|
Mirsadraee, Majid; Mozaffari, Abolfazl & Attaran, Davood
Objective: Exposure of DNA to sulfur mustard gas may increase the inheritance of asthma in
chemical warfare victims' (CWV) offspring. The objective of this study was to determine the
prevalence of asthma in children of CWV and compare it to asthmatic children in the general
Methods: Four hundred and nine children from 130 CWV fathers and 440 children from 145
asthmatic parents from two cities in Iran participated in this study. The prevalence of asthma was
determined by standard questionnaire released for epidemiological survey of asthma in children
and compared between two groups.
Findings: The prevalence of asthma in the CWV group was 15%; this was not significantly different
from the control group (12.5%). The children of the CWV group reported a significantly greater
incidence of wheezing (1.2±3.1 attacks) per year, but the control group reported more severe
attacks leading to speech difficulties (3%) and coughing (7%). Regression analysis showed that
with increasing family size in the control group, the number of subjects suffering from asthmatic
symptoms decreases significantly (r=0.86, P=0.001).
Conclusion: Chemical agents may increase the prevalence of asthma in the offspring of CWV.
Chemical Warfare; Sulfur Mustard Gas; Asthma; Family Size
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