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Iranian Journal of Pediatrics
Tehran University of Medical Sciences Press
ISSN: 1018-4406
EISSN: 2008-2150
Vol. 22, No. 1, 2012, pp. 117-120
Bioline Code: pe12020
Full paper language: English
Document type: Case Report
Document available free of charge

Iranian Journal of Pediatrics, Vol. 22, No. 1, 2012, pp. 117-120

 en Pericardial Effusion and Atrial Thrombosis: A Rare Complication of Childhood Leukemia
Zareifar, Soheila; Cheriki, Sirous; Namdari, Maral; Farahmandfar, Mohammadreza & Jannati, Ahmad


Background: Acute lymphoblastic leukemia (ALL) is the most common malignancy diagnosed in children. Extramedullary leukemia including hepatosplenomegaly, lymphadenopathy, and mediastinal mass are the clinical presentations of T-cell ALL. Pericardial effusion and atrial mass are rare presentations of pediatric leukemia.
Case Presentation: We report a 15-year-old girl with T-cell ALL, who presented initially with pericardial effusion and cardiac tamponade and subsequently developed right atrial mass. The mediastinal and right atrial masses were excised by surgical procedure as a treatment strategy for prevention of arrhythmia and sudden death.
Conclusion: T-cell ALL can present with pericardial and mediastinal involvement as an initial manifestation. Pericardiocenthesis and systemic anticancer chemotherapy without local chemotherapy should be considered in these cases.

Acute Lymphoblastic Leukemia; Extramedullary Leukemia; Pericardial Effusion; Atrial Mass

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