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Iranian Journal of Pediatrics
Tehran University of Medical Sciences Press
ISSN: 1018-4406
EISSN: 2008-2150
Vol. 22, No. 1, 2012, pp. 117-120
Bioline Code: pe12020
Full paper language: English
Document type: Case Report
Document available free of charge

Iranian Journal of Pediatrics, Vol. 22, No. 1, 2012, pp. 117-120

 en Pericardial Effusion and Atrial Thrombosis: A Rare Complication of Childhood Leukemia
Zareifar, Soheila; Cheriki, Sirous; Namdari, Maral; Farahmandfar, Mohammadreza & Jannati, Ahmad

Abstract

Background: Acute lymphoblastic leukemia (ALL) is the most common malignancy diagnosed in children. Extramedullary leukemia including hepatosplenomegaly, lymphadenopathy, and mediastinal mass are the clinical presentations of T-cell ALL. Pericardial effusion and atrial mass are rare presentations of pediatric leukemia.
Case Presentation: We report a 15-year-old girl with T-cell ALL, who presented initially with pericardial effusion and cardiac tamponade and subsequently developed right atrial mass. The mediastinal and right atrial masses were excised by surgical procedure as a treatment strategy for prevention of arrhythmia and sudden death.
Conclusion: T-cell ALL can present with pericardial and mediastinal involvement as an initial manifestation. Pericardiocenthesis and systemic anticancer chemotherapy without local chemotherapy should be considered in these cases.

Keywords
Acute Lymphoblastic Leukemia; Extramedullary Leukemia; Pericardial Effusion; Atrial Mass

 
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