Iranian Journal of Pediatrics
Tehran University of Medical Sciences Press
Vol. 22, No. 2, 2012, pp. 260-264
Bioline Code: pe12046
Full paper language: English
Document type: Case Report
Document available free of charge
Iranian Journal of Pediatrics, Vol. 22, No. 2, 2012, pp. 260-264
© Copyright 2012 - Iranian Journal of Pediatrics
Third-Degree Heart Block in Thalassemia major: A Case Report|
Maleki, Ali R.; Nikyar, Bagher & Hosseini, Seyed M.
Background: First and second-degree heart blocks are partly common rhythm disorders in thalassemic
patients but complete heart block is a very rare complication of iron overload cardiomyopathy.
Case Presentation: This 15-year-old boy, a known case of major β-thalassemia was admitted to our
emergency unit with dyspnea and cough because of decompensated heart failure. The electrocardiogram
showed complete heart block with junctional escape rhythm. Interestingly, his previous electrocardiogram
taken 2 months earlier, had some PVC and second degree, Mobitz type 1 (Wenckebach) heart block. After
improvement of dyspnea and control of blood pressure in normal range, the patient was referred to ER. A
dual-chamber permanent pacemaker was implanted and his symptoms improved, but he died 24 days after
discharge from hospital.
Conclusion: We present a rare case of complete heart block after a second-degree (Mobitz 1) heart block that
was due to severe iron overload cardiomyopathy.
β-Thalassemia, Arrhythmia, Iron overload; Cardiomyopathy
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