Iranian Journal of Pediatrics
Tehran University of Medical Sciences Press
Vol. 22, No. 3, 2012, pp. 290-296
Bioline Code: pe12054
Full paper language: English
Document type: Research Article
Document available free of charge
Iranian Journal of Pediatrics, Vol. 22, No. 3, 2012, pp. 290-296
© Copyright 2012 - Iranian Journal of Pediatrics
Kidney Stones in Children and Teenagers in the Central Coast Region of Tunisia|
Alaya, Akram; Belgith, Mohsen; Hammadi, Saad; Nouri, Abdellatif & Najjar, Mohamed Fadhel
Objective: Since 1980s, the clinical and biological characteristics of urolithiasis in Tunisian children have
continuously evolved. This retrospective study defines the current status of urolithiasis among children and
adolescents in Tunisia.
Methods: We retrospectively reviewed the records of 310 children and adolescents (age: 3 months - 19 years)
between 2003 and 2010, holding urolithiasis. A first-line metabolic, urine and plasma work-up was performed
in all patients. Physical and chemical analysis of the stones was performed respectively by stereomicroscopy
and infrared spectroscopy. Statistical analysis of the results was performed with SPSS 11.0 software. The Chisquare
test was used for comparison of percentages.
Findings: Our study shows a male predominance of urolithiasis with a sex ratio of 1.5. Stones were located in
the upper urinary tract in 70.7% of cases. Calcium oxalate was the predominant constituent in 52.6% of
stones. There was an increasing prevalence of calcium oxalate stones according to age in both genders (48.6%
in infants vs 68.5% in teenagers (P<0.01)). Struvite was more frequent in patients aged 2-9 years (P<0.02)
and significantly more prevalent in boys than in girls (P<0.001). Ammonium urate stones were observed in
14.2% and were more frequent in infants.
Conclusion: Our results emphasize a high percentage of calcium oxalate stones and a low percentage of
struvite stones. The persistence of urate stones reflects the particular eating habits and the infectious risk
factors. The patient’s age is an important factor that must be taken into account during etiopathogenic workup.
Urolithiasis; Teenagers; Infants; Kidney; Tunisia
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