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11-Year Experience with Gastroschisis: Factors Affecting Mortality and Morbidity
Erdoğan, Derya; Azılı, Müjdem Nur; Çavuşoğlu, Yusuf Hakan; Tuncer, İlker SaA; Karaman, İbrahim; Karaman, Ayşe & Özgüner, İsmet Faruk
Abstract
Objective: The aim of the study was the evaluation of patients treated with a diagnosis of gastroschisis and to
establish the factors which affected the morbidity and mortality.
Methods: Twenty-nine patients, managed for gastroschisis during 2000-2010 were reviewed retrospectively.
Patients were analysed in respect to gestational age, birth weight, associated anomalies, type of delivery,
operative procedures, postoperative complications, total parenteral nutrition (TPN) related complications.
The factors affecting mortality and morbidity were determined.
Findings: Associated abnormalities were present in 24% of the patients. Eleven patients underwent elective
reduction in the incubator (Bianchi procedure) without anesthesia. Eight patients had delayed reduction with
silo and ten patients had primary closure. Although the type of delivery had an effect on morbidity but not
mortality, gestational age, birth weight, and the operative procedure performed had no effect on morbidity or
mortality. Duration until tolerance of oral intake, and of TPN and hospitalization were found to be statistically
significantly shorter in the group of babies delivered by cesarean section.
Conclusion: In our study the most important cause of mortality was the abdominal compartment syndrome
and multi-organ failure in the early years. Long hospitalization periods and sepsis were the main causes of
mortality in recent years.
Keywords
Gastroschisis; Morbidity; Mortality; Neonate
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