Iranian Journal of Pediatrics
Tehran University of Medical Sciences Press
Vol. 22, No. 3, 2012, pp. 364-368
Bioline Code: pe12066
Full paper language: English
Document type: Research Article
Document available free of charge
Iranian Journal of Pediatrics, Vol. 22, No. 3, 2012, pp. 364-368
© Copyright 2012 - Iranian Journal of Pediatrics
Dysbiosis in Ukrainian Children with Irritable Bowel Syndrome Affected by Natural Radiation|
Sajjadieh, Mohammad-Reza Sheikh; Kuznetsova, Larisa V & Bojenko, Vadim B
Objective: Microbiota has an important role in human metabolism, nutrition, immunity, and protection
against colonization by pathogenic microorganisms. Radiation can harm the beneficial members of the
gastrointestinal tract flora.
Methods: Our study included 75 rural children aged 4-18 years, who lived in contaminated area exposed to
natural environmental radiation with clinical symptoms of irritable bowel syndrome and 20 healthy urban
participants aged 5-15 as control group. The intestinal bacterial microbiota was examined from stool samples.
Findings: Our results indicated the population levels of microbiota such as Enterobacter, Enterococcus,
Lactobacillus and Bifidbacterium in caecal contents in 61 subjects (81.3%) was significantly less than in
Conclusion: We investigated alternation of the intestinal microbiota affected by ionizing radiation in children
with clinical symptoms of irritable bowel syndrome.
Microbiota; Immune Status; Irritable Bowel Syndrome
Alternative site location: http://diglib.tums.ac.ir/pub/