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Iranian Journal of Pediatrics
Tehran University of Medical Sciences Press
ISSN: 1018-4406
EISSN: 2008-2150
Vol. 22, No. 3, 2012, pp. 364-368
Bioline Code: pe12066
Full paper language: English
Document type: Research Article
Document available free of charge

Iranian Journal of Pediatrics, Vol. 22, No. 3, 2012, pp. 364-368

 en Dysbiosis in Ukrainian Children with Irritable Bowel Syndrome Affected by Natural Radiation
Sajjadieh, Mohammad-Reza Sheikh; Kuznetsova, Larisa V & Bojenko, Vadim B

Abstract


Objective: Microbiota has an important role in human metabolism, nutrition, immunity, and protection against colonization by pathogenic microorganisms. Radiation can harm the beneficial members of the gastrointestinal tract flora.
Methods: Our study included 75 rural children aged 4-18 years, who lived in contaminated area exposed to natural environmental radiation with clinical symptoms of irritable bowel syndrome and 20 healthy urban participants aged 5-15 as control group. The intestinal bacterial microbiota was examined from stool samples.
Findings: Our results indicated the population levels of microbiota such as Enterobacter, Enterococcus, Lactobacillus and Bifidbacterium in caecal contents in 61 subjects (81.3%) was significantly less than in control group.
Conclusion: We investigated alternation of the intestinal microbiota affected by ionizing radiation in children with clinical symptoms of irritable bowel syndrome.

Keywords
Microbiota; Immune Status; Irritable Bowel Syndrome

 
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