Iranian Journal of Pediatrics
Tehran University of Medical Sciences Press
Vol. 22, No. 4, 2012, pp. 481-486
Bioline Code: pe12089
Full paper language: English
Document type: Research Article
Document available free of charge
Iranian Journal of Pediatrics, Vol. 22, No. 4, 2012, pp. 481-486
© Copyright 2012 - Iranian Journal of Pediatrics
Validation of Pediatric Index of Mortality-2 Scoring System in a Single Pediatric Intensive Care Unit in Iran|
Salamati, Payman; Talaee, Saeed; Eghbalkhah, Asgar; Chaman, Reza; Mokhtari, Zahra & Azarshahin, Mitra
Objective: A study to validate and calibrate Pediatric Index of Mortality-2 (PIM2) in children admitted to our
pediatric intensive care unit (PICU).
Methods: This is a prospective cohort study performed in Bahrami Children’s Hospital affiliated to Tehran
University of Medical Sciences. We studied the patients admitted to PICU from May 2007 to November 2008.
Clinical measures were identified upon arrival in PICU. We used PIM2 score and logistic regression analysis to
compare expected mortality risk with observed mortality rate. Receiver operating characteristics (ROC) curve
analysis was done and standardized mortality ratio was calculated. PIM2 Index assessment was performed by
use of Hosmer and Lemeshow goodness-of-fit test.
Findings: 240 patients were included in this study. The model fit was achieved adequately (P value = 0.741).
The area under the ROC curve was 0.795 (0.715-0.875 for 95% confidence interval) and standardized
mortality ratio was 1.8 (1.28-2.465 for 95% confidence interval) High-risk group diagnosis with adjusted
odds ratio (AOR)=14.75, pupil reaction to light (AOR=0.13) and duration of stay in PICU (AOR=1.03) had
significant statistical association to pediatric mortality.
Conclusion: PIM2 is a good index for prediction of mortality in our pediatric intensive care unit. This study
revealed that there is significant statistical association between the children mortality and the length of
hospitalization, pupillary light reflex and the risk level category on admission.
Mortality; Pediatric intensive care unit; Pediatric Index of Mortality-2 (PIM2); Iran
Alternative site location: http://diglib.tums.ac.ir/pub/