Iranian Journal of Pediatrics
Tehran University of Medical Sciences Press
Vol. 23, No. 4, 2013, pp. 411-416
Bioline Code: pe13079
Full paper language: English
Document type: Research Article
Document available free of charge
Iranian Journal of Pediatrics, Vol. 23, No. 4, 2013, pp. 411-416
© Iranian Journal of Pediatrics
Long-Term Results of Transcatheter Closure of Patent Ductus Arteriosus in Infants Using Amplatzer Duct Occluder|
Behjati-Ardakani, Mostafa; Behjati-Ardakani, Mohammad-Amin; Hosseini, Seyed-Habibolla & Noori, Noormohammad
Objective: Patent ductus arteriosus (PDA) is one of the most frequently seen congenital heart diseases. Its
closure is recommended because of the risk of infective endocardis, as well as morbidity and mortality in the
long. The aim of this study was to assess the long term results of the transcatheter closure of PDA in infants
using amplatzer duct occlude (ADO).
Methods: From May 2004 to September 2011, forty eight infants underwent transcatheter closure of PDA.
A lateral or right anterior oblique view aortogram was done to locate PDA and to measure its size. Before
discharge, repeat aortogram was performed to evaluate eventual residual shunt and to confirm the
appropriate deployment of the ADO. Follow up evaluations were done with transthoracic echocardiography at
discharge, 1 month, 6 months, 12 months and yearly thereafter.
Findings: The mean age of patients at procedure was 9.18±2.32 (range 3 to 12) months, mean weight
6.73±1.16 (range 4.5 to 10.1) kg. The PDA occluded completely in 20 out of the 48 patients. Twenty four
patients had trivial or mild shunt and two patients had moderate residual shunt which disappeared in one
patient within 24 hours and other patient with moderate shunt in 1 month. One patient (age 8 months) had
mild LPA stenosis. The device emobolization occurred in two patients, immediately after the procedure in one
and during night in the other patient
Conclusion: The long term results suggested that transcatheter closure of PDA using Amplatzer duct occluder
is a safe and effective treatment in infants less than 1 year of age with minimal complications.
Patent Ductus Arteriosus; Transcatheter Closure; Congenital Heart Defect
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