Cost-Utility Analysis of Neonatal Screening Program, Shiraz University of Medical Sciences, Shiraz, Iran, 2010|
Hatam, Nahid; Shirvani, Samad; Javanbakht, Mehdi; Askarian, Mehrdad & Rastegar, Mohsen
Objective: The most important cause of infant mortality during the first month of life is related to congenital
abnormalities. Nevertheless, timely diagnosis of these diseases can reduce the severity of their effects. The
present study aimed to investigate the cost-effectiveness of the neonatal screening program in Fars Province,
Methods: In this study, costs of executing the screening programs, treatment of the diagnosed cases,
treatment of affected, non-screened individuals, quality of life, and incremental cost-effectiveness ratios were
measured in two study groups.
Findings: Performing the screening programs for phenylketonuria, congenital hypothyroidism, galactosemia,
and favism resulted in respectively $3386, $13078, $19641, and $1088 saving per patient. Overall, the study
results revealed the cost-effectiveness of execution of the neonatal screening program.
Conclusion: Neonatal screening program is one of the health interventions which lead to long-term beneficial
outcome for the patients, financial saving for the society, and improvement of the patients’ quantity as well as
quality of life.
Cost-utility Analysis; Screening, Economic Evaluation; Phenylketonuria; Congenital Hypothyroidism; Favism; Galactosemia