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Iranian Journal of Pediatrics
Tehran University of Medical Sciences Press
ISSN: 1018-4406
EISSN: 2008-2150
Vol. 24, No. 5, 2014, pp. 565-568
Bioline Code: pe14090
Full paper language: English
Document type: Review Article
Document available free of charge

Iranian Journal of Pediatrics, Vol. 24, No. 5, 2014, pp. 565-568

 en Metformin and Diabetic Kidney Disease: A Mini-Review on Recent Findings
Nasri, Hamid & Rafieian-Kopaei, Mahmoud

Abstract

Metformin, an oral anti-diabetic agent in the biguanide class is a widely prescribed drug to treat high blood glucose in patients with type 2 diabetes mellitus. Metformin has three different roles, including blood glucose regulatory effect, protection of kidney tubular cell by acting as an effective antioxidant and finally ameliorative effect on diabetic kidney disease through saving the podocytes. Therefore, diabetic patients may benefit from all of these three distinct ameliorative effects.

Keywords
Metformin; Kidney Disease; Diabetes; Anti-diabetic Agents

 
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