Iranian Journal of Pediatrics
Tehran University of Medical Sciences Press
Vol. 25, No. 4, 2015, pp. 1-4
Bioline Code: pe15052
Full paper language: English
Document type: Research Article
Document available free of charge
Iranian Journal of Pediatrics, Vol. 25, No. 4, 2015, pp. 1-4
© Copyright - 2015 Iranian Journal of Pediatrics
An Evaluation of Oxidative Status in Serum and Breast Milk of Mothers Giving Birth Prematurely and at Full-Term|
Abuhandan, Mahmut; Demir, Nihat; Guzel, Bulent; Almaz, Veysi; Koca, Bulent; Tuncer, Oguz & Cakmak, Alpay
Background: Burning fat and carbohydrates to provide energy in biological systems causes the formation of free oxygen species.
Objectives: This study aimed to evaluate the oxidative status of serum and breast milk of mothers giving birth prematurely and at full-term.
Materials and Methods: The study comprised 50 mothers who gave birth at full-term at more than 38 weeks and 43 mothers who gave birth pre-term at below 32 weeks. On the postnatal 5th day, samples of the mother’s milk and serum were taken and stored at -80°C until the study day. On the study day, the total oxidant and total antioxidant levels were measured using the Erel method and the oxidative stress index (OSI) was calculated.
Results: While the total oxidant level and total antioxidant level values of the milk of the premature birth mothers were found to be significantly high compared to those of the full-term birth mothers (P = 0.001), no statistically significant difference was found in the oxidative stress index values (P > 0.05). No statistically significant difference was found in the total oxidant level and oxidative stress index values of the serum of the premature birth mothers compared to those of the full-term birth mothers, while the total antioxidant level was found to be significantly low (P = 0.04).
Conclusions: The oxidants and antioxidants in the milk of mothers giving birth prematurely were found to be significantly higher than those of full-term birth mothers. This can be evaluated as the milk of the premature birth mothers providing increased antioxidant defense to protect the infant.
Antioxidants; Mother; Breast milk
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