|
Iranian Journal of Pediatrics
Tehran University of Medical Sciences Press
ISSN: 1018-4406 EISSN: 1018-4406
Vol. 27, No. 1, 2017, pp. 1-6
|
Bioline Code: pe17011
Full paper language: English
Document type: Research Article
Document available free of charge
|
|
Iranian Journal of Pediatrics, Vol. 27, No. 1, 2017, pp. 1-6
en |
Effects of Phototherapy on Antioxidant Status of Preterm and Term Infants with Hyperbilirubinemia
Tekgündüz, Kadir Şerafettin; Gürol, Ayşe; Kurt, Nezahat & Apay, Serap Ejder
Abstract
Objectives: The primary purpose of this study was to investigate the effects of phototherapy on antioxidant status of preterm and
term infants with hyperbilirubinemia.
Methods: Term and preterm infants were divided to three groups; group 1: 28 to < 32 weeks, group 2: 32 to < 37 weeks, and group
3: term infants hospitalized due to jaundice requiring phototherapy during the first to ninth day of life . Fifty-six infants were included
in this study. Levels of serum total bilirubin, malondialdehyde, superoxide dismutase, reduced glutathione and catalase
were measured before and 24 hours after phototherapy.
Results: It was found that the reduced glutathione levels in group 1 including preterm infants decreased significantly after phototherapy.
It was observed that levels of malondialdehyde increased significantly in term infants compared to preterm infants in
group 1 and group 2. It was observed that the decreases in bilirubin and superoxide dismutase enzyme were correlated in group 2
preterm infants and group 3 term infants. Conclusions: Phototherapy did not significantly affect the antioxidant level in the present study. The fact that there was a significant
decrease in glutathione peroxidase levels after phototherapy only in group 1 preterm infants suggests that more attention should
be paid when phototherapy is used in this age group.
Keywords
Antioxidants; Hyperbilirubinemia; Infants; Phototherapy; Preterm
|
|
© Copyright 2017 - Growth and Development Research Center Alternative site location: http://diglib.tums.ac.ir/pub/
|
|