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Indian Journal of Pharmacology
Medknow Publications on behalf of Indian Pharmacological Society
ISSN: 0253-7613
EISSN: 0253-7613
Vol. 40, No. 1, 2008, pp. 28-31
Bioline Code: ph08007
Full paper language: English
Document type: Research Article
Document available free of charge

Indian Journal of Pharmacology, Vol. 40, No. 1, 2008, pp. 28-31

 en Antiasthmatic activity of Moringa oleifera   check for this species in other resources Lam: A clinical study
Agrawal, Babita & Mehta, Anita

Abstract

The present study was carried out to investigate the efficacy and safety of seed kernels of Moringa oleifera   check for this species in other resources in the treatment of bronchial asthma. Twenty patients of either sex with mild-to-moderate asthma were given finely powdered dried seed kernels in dose of 3 g for 3 weeks. The clinical efficacy with respect to symptoms and respiratory functions were assessed using a spirometer prior to and at the end of the treatment. Hematological parameters were not changed markedly by treatment with M. oleifera . However, the majority of patients showed a significant increase in hemoglobin (Hb) values and Erythrocyte sedimentation rate (ESR) was significantly reduced. Significant improvement was also observed in symptom score and severity of asthmatic attacks. Treatment with the drug for 3 weeks produced significant improvement in forced vital capacity, forced expiratory volume in one second, and peak expiratory flow rate values by 32.97 ± 6.03%, 30.05 ± 8.12%, and 32.09 ± 11.75%, respectively, in asthmatic subjects. Improvement was also observed in % predicted values. None of the patients showed any adverse effects with M. oleifera . The results of the present study suggest the usefulness of M. oleifera seed kernel in patients of bronchial asthma.

Keywords
Bronchial asthma, Moringa oleifera, pulmonary function tests

 
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