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Indian Journal of Pharmacology
Medknow Publications on behalf of Indian Pharmacological Society
ISSN: 0253-7613
EISSN: 0253-7613
Vol. 41, No. 1, 2009, pp. 47-48
Bioline Code: ph09011
Full paper language: English
Document type: Case Report
Document available free of charge

Indian Journal of Pharmacology, Vol. 41, No. 1, 2009, pp. 47-48

 en Emergence of pristinamycin resistance in India
Keshari, Shyam Sunder; Kapoor, Arun Kumar; Kastury, Nira; Singh, Dharmendra Kumar & Bhargava, Anudita

Abstract

Quinupristin and dalfopristin combination has been advocated as a drug of choice for multi-drug resistant (MDR) gram-positive cocci (GPC). We are reporting two cases of neonatal septicemia, caused by the methicillin resistant Staphylococcus aureus check for this species in other resources (MRSA), showing primary in vitro pristinamycin resistance. The Minimum inhibitory concentrations (MIC) for pristinamycin in these two cases were 30 µg and 25 µg, respectively. Universal advocacy of pristinamycin for the therapy of MDR GPC infections should be re-evaluated.

Keywords
Dalfopristin/quinupristin, pristinamycin resistance, staphylococcus

 
© Copyright 2009 Indian Journal of Pharmacology.
Alternative site location: http://www.ijp-online.com

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