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Indian Journal of Pharmacology
Medknow Publications on behalf of Indian Pharmacological Society
ISSN: 0253-7613
EISSN: 0253-7613
Vol. 42, No. 1, 2010, pp. 2-8
Bioline Code: ph10002
Full paper language: English
Document type: Special Article
Document available free of charge

Indian Journal of Pharmacology, Vol. 42, No. 1, 2010, pp. 2-8

 en Angiogenesis: Future of pharmacological modulation
Bisht, Manisha; Dhasmana, D. C. & Bist, S. S.

Abstract

Angiogenesis is a fundamental biological process that is regulated by a fine balance between pro- and antiangiogenic molecules, and is deranged in various diseases. Historically, angiogenesis was only implicated in few diseases, such as, cancer, arthritis, and psoriasis. However, in recent years, it has been increasingly evident that excessive, insufficient or abnormal angiogenesis contributes to the pathogenesis of many more disorders. Research in angiogenesis offers a potential to cure a variety of diseases such as Alzheimer′s and AIDS. Modulation of angiogenesis may have an impact on diseases in the twenty-first century similar to that which the discovery of antibiotics had in the twentieth century.

Keywords
Angiogenesis, antiangiogenic drugs, vascular endothelial growth factor

 
© Copyright 2010 Indian Journal of Pharmacology.
Alternative site location: http://www.ijp-online.com

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