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Indian Journal of Pharmacology
Medknow Publications on behalf of Indian Pharmacological Society
ISSN: 0253-7613
EISSN: 1998-3751
Vol. 42, No. 3, 2010, pp. 189-191
Bioline Code: ph10053
Full paper language: English
Document type: Case Report
Document available free of charge

Indian Journal of Pharmacology, Vol. 42, No. 3, 2010, pp. 189-191

 en Zidovudine-induced reversible pure red cell aplasia
Balakrishnan, Anuja; Valsalan, Rohith; Sheshadri, Shubha; Pandit, Vinay R.; Medep, Vikas & Agrawal, Ravindra Kumar

Abstract

Hematological abnormalities are frequent among human immunodeficiency virus (HIV)-infected patients and may be directly attributable to the virus or may be caused by opportunistic infections, neoplasms or drugs that cause bone marrow suppression or hemolysis. Pure red cell aplasia (PRCA) is an uncommon hematological disorder that causes anemia. We report a 37-year-old male with HIV infection who developed PRCA 6 weeks after commencing Zidovudine and recovered following cessation of the drug. This is the first case of Zidovudine-induced PRCA reported from the Indian subcontinent.

Keywords
HIV, pure red cell aplasia, Zidovudine

 
© Copyright 2010 Indian Journal of Pharmacology.
Alternative site location: http://www.ijp-online.com

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