Indian Journal of Pharmacology
Medknow Publications on behalf of Indian Pharmacological Society
Vol. 42, No. 3, 2010, pp. 189-191
Bioline Code: ph10053
Full paper language: English
Document type: Case Report
Document available free of charge
Indian Journal of Pharmacology, Vol. 42, No. 3, 2010, pp. 189-191
© Copyright 2010 Indian Journal of Pharmacology.
Zidovudine-induced reversible pure red cell aplasia|
Balakrishnan, Anuja; Valsalan, Rohith; Sheshadri, Shubha; Pandit, Vinay R.; Medep, Vikas & Agrawal, Ravindra Kumar
Hematological abnormalities are frequent among human immunodeficiency virus (HIV)-infected patients and may be directly attributable to the virus or may be caused by opportunistic infections, neoplasms or drugs that cause bone marrow suppression or hemolysis. Pure red cell aplasia (PRCA) is an uncommon hematological disorder that causes anemia. We report a 37-year-old male with HIV infection who developed PRCA 6 weeks after commencing Zidovudine and recovered following cessation of the drug. This is the first case of Zidovudine-induced PRCA reported from the Indian subcontinent.
HIV, pure red cell aplasia, Zidovudine
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