Objective : In this work, we report the antibacterial and modulatory activity of
Lantana montevidensis
Briq.
Materials and Methods : The antibacterial activities of leaf (LELm) and root (RELm) extracts alone or in association with aminoglycosides were determined by a microdilution test. Multiresistant strains of
Escherichia coli
(Ec 27) and
Staphylococcus aureus
(Sa 358) were used.
Results : The results show the inhibitory activity of LELm against
E. coli (minimal inhibitory concentration [MIC] 16 μg/mL) and S. aureus (MIC 128 μg/mL). The synergistic effect of the extracts and aminoglycosides was verified too. The maximum effects were obtained with RELm with gentamicin against
E. coli with MIC reduction (312 to 2 μL).
Conclusion : The data from this study are indicative of the activity antibacterial of extracts of
L. montevidensis and its potential in modifying the resistance of aminoglycosides.
