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Indian Journal of Plastic Surgery
Medknow Publications on behalf of Indian Journal of Plastic Surgery
ISSN: 0970-0358 EISSN: 0970-0358
Vol. 36, No. 1, 2003, pp. 14-17
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Bioline Code: pl03003
Full paper language: English
Document type: Research Article
Document available free of charge
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Indian Journal of Plastic Surgery, Vol. 36, No. 1, 2003, pp. 14-17
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Preparation of two component Fibrin Glue and its clinical evaluation in skin grafts and flaps
Samir Saxena, Pradeep Jain, Jyoti Shukla
Abstract
Tissue adhesive is one of the alternative to conventional suturing and has some added advantages. Fibrin glue has been used in obtaining haemostasis following trauma to spleen and liver. It has also been used in repair of dural tear and bronchial fistula. Fibrin glue is a biological tissue adhesive based on the final stage of coagulation wherein. Thrombin acting on fibrinogen converts it into fibrin. Thus, it has two components, one is fibrinogen and another is thrombin. We have prepared both components of fibrin glue. Fibrinogen was obtained from patient's own blood and thrombin from fresh frozen plasma of screened healthy donor. The glue was used in 20 cases requiring skin graft or flap. The results were compared with conventional suturing method. Use of the fibrin glue is simple, safe, cost effective, and rapid technique to fix the skin grafts and flaps with avoidance of peroperative bleeding and postoperative collection. It also has better overall results.
Keywords
Fibrin Glue, Plastic Surgery, Fixation of Skin Grafts & Flaps
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