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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996
EISSN: 1596-9827
Vol. 5, No. 1, 2006, pp. 551-555
Bioline Code: pr06005
Full paper language: English
Document type: Research Article
Document available free of charge

Tropical Journal of Pharmaceutical Research, Vol. 5, No. 1, 2006, pp. 551-555

 en Efficacy of artemether-lumfantrine (Co-Artesiane®) suspension in the treatment of uncomplicated Plasmodium falciparum malaria among children under 5 years in eastern Sudan
Muntaisr T. Salah, Mohamed Faroug, Mamoum M. Magzoub, Ishag Adam

Abstract

Purpose: the aim of the present study was to investigate the efficacy of artemether-lumfantrine (Co-Artesiane®) suspension for the treatment of uncomplicated Plasmodium falciparum malaria in children (aged 6-59 months) in Kassala in eastern Sudan.
Method: This was a prospective clinical trial where the artemether-lumfantrine (Co-Artesiane®) suspension was given for three days and the patients were followed-up for 28 days
Results: Forty-eight patients were enrolled in the study and 43 of them completed the 28-days follow-up. Treatment rapidly cleared parasitemia and fever. The overall 28-day cure rate was 100% and no clinical or parasitological failures were observed among these patients. Mild side effects were observed in three (7%) children.
Conclusion: Artemether-lumfantrine (coartem) suspension appears to be efficacious and safe for the treatment of uncomplicated malaria.

Keywords
Artemether-lumfantrine, Co-Artesiane, children, falciparum, malaria, Sudan

 
© Copyright 2006. TJPR Faculty of Pharmacy, University of Benin, Benin City, Nigeria
Alternative site location: http://www.tjpr.org

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