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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996
EISSN: 1596-5996
Vol. 6, No. 4, 2007, pp. 809-813
Bioline Code: pr07023
Full paper language: English
Document type: Research Article
Document available free of charge

Tropical Journal of Pharmaceutical Research, Vol. 6, No. 4, 2007, pp. 809-813

 en Antimicrobial activity of the ethanol extract of the aerial parts of sida acuta check for this species in other resources burm.f. (malvaceae)
Oboh, I.E.; Akerele, J.O. & Obasuyi, O.

Abstract

Purpose: The antimicrobial activity of the 90 % ethanol extract of the aerial parts of sida acuta check for this species in other resources Burm. F. (Malvaceae) was investigated in other to verify its claimed ethno medicinal use in the treatment of microbial infections.
Method: The antimicrobial activity of the extract was tested against standard strains and clinical isolates of some aerobic bacteria and a fungus using the Agar well diffusion method. Commercial antibiotics were used as positive reference standards to determine the sensitivity of the strains.
Results: The extracts showed significant inhibitory activity against standard strains and clinical isolates of Staphylococcus aureus, clinical isolates of Bacillus subtilis and Streptococcus faecalis. The MIC values obtained using the Agar-dilution test ranged from 5.0 mg/ml. -10.0 mg/ml. Neither the concentrated extract nor its dilutions inhibited Escherichia coli check for this species in other resources , Klebsiella pneumonia check for this species in other resources , Pseudomonas aeruginosa check for this species in other resources and Candida albicans check for this species in other resources
Conclusion: The results demonstrate that the crude extract of the aerial parts of Sida acuta has a narrow spectrum of activity and suggest that it may be useful in the treatment of infections caused by Gram positive aerobic bacteria.

Keywords
Sida acuta, ethanol extract, antimicrobial activity.

 
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