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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996
EISSN: 1596-5996
Vol. 7, No. 3, 2008, pp. 1051-1054
Bioline Code: pr08026
Full paper language: English
Document type: Report
Document available free of charge

Tropical Journal of Pharmaceutical Research, Vol. 7, No. 3, 2008, pp. 1051-1054

 en Antifungal Activity of Endemic Salvia tigrina check for this species in other resources in Turkey
Dulger, B. & Hacioglu, N.

Abstract

Purpose: The ethanol extracts obtained from the leaves, rootstock and the combined formulation of endemic Salvia tigrina check for this species in other resources Hedge & Hub.-Mor. (Labiatea) have been investigated for their antifungal activities.
Method: The antifungal activity of the extract was tested against Candida check for this species in other resources species (C. albicans ATCC 10231, C. tropicalis ATCC 13803 and C. guilliermondii ATCC 6260 and Cryptococcus check for this species in other resources species (C. neoformans ATCC 90112 and C. laurentii 34142), Aspergillus flavus check for this species in other resources , Penicillium frequentans check for this species in other resources , Botrytis cinerea check for this species in other resources , Geotrichum candidum check for this species in other resources , Fusarium oxysporum check for this species in other resources and Alternaria alternara check for this species in other resources by the visual broth macrodilution method. Ketoconazole was used as a positive reference standard to determine the sensitivity of the strains.
Results: The minimum inhibitory concentration (MIC) ranged from 3.12 to 25 mg/mL. All the extracts exhibited a strong antifungal effect against the fungal cultures. The extracts exhibited greater antifungal effect against C. albicans, C. neoformans and B. cinarea.
Conclusion: The findings provide support for the use of this plant in traditional medicine for fungal infections especially against candidiasis.

Keywords
Antifungal activity, Salvia tigrina, Plant extracts, Minimum inhibitory concentration

 
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