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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996
EISSN: 1596-9827
Vol. 8, No. 5, 2009, pp. 455-465
Bioline Code: pr09059
Full paper language: English
Document type: Research Article
Document available free of charge

Tropical Journal of Pharmaceutical Research, Vol. 8, No. 5, 2009, pp. 455-465

 en Phytochemical Constituents and Pharmacological Activities of Calendula officinalis check for this species in other resources Linn (Asteraceae): A Review
Muley, B.P.; Khadabadi, S.S. & Banarase, N.B.

Abstract

Calendula officinalis check for this species in other resources Linn. (Asteraceae) is used medicinally in Europe, China and India amongst several places in the world. It is also known as "African marigold" and has been a subject of several chemical and pharmacological studies. It is used in traditional medicine, especially for wound healing, jaundice, blood purification, and as an antispasmodic. Chemical studies have underlined the presence of various classes of compounds, the main being triterpenoids, flavonoids, coumarines, quinones, volatile oil, carotenoids and amino acids. The extract of this plant as well as pure compounds isolated from it, have been demonstrated to possess multiple pharmacological activities such as anti-HIV, cytotoxic, antiinflammatory, hepatoprotective, spasmolytic and spasmogenic, amongst others. In this review, we have explored the phytochemistry and pharmacological activities of C. officinalis in order to collate existing information on this plant as well as highlight its multi-activity properties as a medicinal agent. This is as a result of the worldwide cultivation of the plant and increasing published reports on it.

Keywords
Calendula officinalis, Asteraceae, Phytochemical constituents, Pharmacological activities, Contraindications.

 
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