Purpose: Ornithogalum sintenisii
is an Iranian species with little known about its pharmacological
effects. The purpose of the present study was to investigate some antioxidant properties of the plant.
The antioxidant potency of the freeze-dried methanol extract of O. sintenisii
bulbs and aerial
parts were investigated by evaluating the following parameters: linoleic acid peroxidation, 1,1-diphenyl-
2-picryl hydrazyl radical (DPPH), scavenging of nitric oxide and hydrogen peroxide as well as reducing
power and Fe2+
chelating activity, using standard methods. Phenol and flavonoid contents were
determined as gallic acid and quercetin equivalents, respectively.
The aerial parts contained higher phenol and flavonoid contents than the bulbs. IC50
radical-scavenging activity was 368 ± 15 and 669 ± 25 μg ml-1
for aerial parts and bulbs, respectively.
The reducing power of the extracts was less than that of vitamin C (p < 0.01) with the aerial parts
showing stronger activity than the bulbs (p < 0.01). The extracts did not show any activity in the
peroxidation test but displayed good H2
radical scavenging activity compared with quercetin (IC50
52.0± 3.1 μg ml-1
) which was used as positive control.
The bulb and aerial parts of O. sintenisii
aerial parts (at flowering stage) exhibited good but
varying levels of antioxidant activities in nearly all the models studied.