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Tropical Journal of Pharmaceutical Research
Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
ISSN: 1596-5996
EISSN: 1596-9827
Vol. 10, No. 3, 2011, pp. 243-248
Bioline Code: pr11032
Full paper language: English
Document type: Research Article
Document available free of charge

Tropical Journal of Pharmaceutical Research, Vol. 10, No. 3, 2011, pp. 243-248

 en Diuretic Activity of Rubus idaeus check for this species in other resources L (Rosaceae) in Rats
Zhang, Ying; Yang, Yinnan; Zu, Xiaoyan; Guan, Di & Wang, Yuepeng

Abstract

Purpose: To evaluate the diuretic activity of Rubus idaeus check for this species in other resources L in experimental rats.
Methods: Hot-water and methanol extract of three kinds of Rubus idaeus L. fruits were administered to experimental rats orally at a dose of 2 and 5 mg/kg. Hydrochlorothiazide (10 mg/kg) was used as positive control in study. The diuretic effect of the extracts was evaluated by measuring urine volume, sodium and potassium excretion in the urine.
Results: Compared with the control group, significant increase in urine volume was observed from the experimental animal treated with wild raspberry methanol extract. In addition, we find that the methanol extract of wild raspberry fruits shows a potassium-conservation diuretic effect, which is a very interesting property in a phytodiuretic.
Conclusion: Methanol extract of wild raspberry fruits have diuretic effect on experimental rats. This might be the first formal reports on diuretic effect of raspberry fruits, which can also, to some extent, explain the use of raspberry as a cure for renal diseases in Chinese traditional medical practice.

Keywords
Diuretic activity, Rubus idaeus L., Rasberry, Herbal medicine

 
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